Global Presence

Porton J-STAR

Solving Complex Chemistry Problems with Creative Solutions for 30+ Years

3001 Hadley Road, Suites 1-5A, South Plainfield, NJ 07080, USA 6 Cedarbrook Dr, Cranbury Township, NJ 08512, USA

30+Years

Founded in 1996, J-STAR Research, Inc. is a contract chemistry R&D organization serving as an outsourcing partner for the pharmaceutical and biotechnology industry.

12,000m²Area

We have steadily added, and continues to expand, in the areas of Process Chemistry, Analytical R&D, QC/QA, GMP delivery, Crystallization R&D, Solid States Screening, Catalysis Screening, Enabling Technologies, High Potent Compound Handling (HPAPI), Impurity Isolation and Structural Elucidation, Pre-formulation, Formulation R&D and Oral Solid Drug Product GMP manufacturing.

60%Doctor Degree

Porton J-STAR has assembled a team of chemists, scientists and engineers committed to creatively solving complex and matrixed chemistry problems. The emphasis of this support is focused on chemistry-related problem solving centered on Active Pharmaceutical Ingredients and Intermediates in the preclinical and clinical development arena.

Facilities

J-STAR South Plainfield R&D Site J-STAR Cranbury R&D Site

J-STAR South Plainfield R&D Site

34 Fume Hoods in Seven Laboratories
2 GMP Kilo Labs with ChemGlass Reactors – up to 100L
2 Analytical Suites for On-Site Method Development and Release Testing
Hydrogenation Room – up to 20L Capacity at 1500 psi
2 High Field NMRs On-Site (400 MHz and 300 MHz)
Multiple HPLC + GC + LC/MS Instruments for Routine Walk-Up Access
Catalysis & Enabling Technology Hub
Scheduled Compound (II-IV) Handling

J-STAR Cranbury R&D Site

34 Fume Hoods in multiple laboratories
4 Walk in Kilo lab Walk-in Hoods with up to 100 L Vessel Processing
1 High Potency Compound Handling Suite with 2 Isolators: cGMP Compliant in 2018
1 Analytical Suite for On-Site Method Development and Release Testing
1 Quality Control Suite for Release Testing
2 High Field NMRs on Site (500 MHz with Cryo probe and 400 MHz)
Multiple HPLC + GC + LC/MS Instruments for Routine Walk-Up Access
Crystallization R&D
Preformulation and Formulation
High Resolution Orbitrap UPLC-MS
Structural Elucidation Hub

Services

Drug Substance High Potent API & Potent Compounds Drug Product R&D and GMP Manufacturing Crystallization & Material Science Analytical R&D and QC

Drug Substance

Porton offers efficient, flexible, and high-quality solutions for custom development and production of small molecule APIs, as well as technical services throughout the entire lifecycle from pre-clinical to commercial to our worldwide partners.

Route Scouting/Design, Early and Late Phase process R&D; GMP Delivery
Impurity Isolation Synthesis
HPAPI, ADC Linker and Payload
Catalysis & Flow Chemistry Technologies

High Potent API & Potent Compounds

Optimized HPAPIs, ADCs and potent compounds development and manufacturing (non-GMP and cGMP) tailored to your specific needs in our new 3000 sq facility equipped with Glovebox Workstations (Isolators) capable of less than 30 ng/m containment.

1)GMP Facilities:

OEB 5 (<1 μg/m³)
Bench & Walk-In Hoods
Up to 100 L Vessels
Prep HPLC and Lyophilizer
Mobile Gloveboxes
Flexible Single-Use-Systems for Powder Handling

2)non-GMP Facilities:

OEB 5 (<1 μg/m³)
Extract-Walker Barrier Isolators: 2
HPAPI Linear Glove Box Feet: 2*8

Drug Product R&D and GMP Manufacturing

At our state-of-art R&D laboratory and expansive 5,100 sq ft GMP facility, we provide tailored drug product development services designed to fast-track the advancement of your Phase I and II drug products.

Comprehensive Formulation Development
Clinical Trial Material Manufacturing
Enabling Formulation Technologies
Solubility Enhancement and Bioavailability Optimization
DS-DP Co-processing

Crystallization & Material Science

We offer fast, effective, phase appropriate and first-time right solutions which are based on scientific understanding to challenges in solid form and crystallization process by utilizing our technical expertise and extensive experience in the industry.

Crystallization Process Development
Particle Engineering
Solid Form Screen/Selection/Studies
Pre-formulation Evaluation

Analytical R&D and QC

We provide Analytical development and QC expertise at all stages of DS and DP development. With tailored workflows, advanced instrumentation, and a team of expert scientists, we deliver actionable insights that enhance product quality, reduce development timelines, and ensure regulatory compliance.

Analytical Development and QC
Method Validation
Stability Study
Structural Elucidation

One Porton One Quality

Compliance standards, Continuous improvement, Customer oriented

Quality management runs throughout the entire process of the drug life cycle. The quality management system of the drug product site is built in accordance with international standards and continues to adhere to the quality concept of 'more well-established system, more controllable quality.' This ensures that the GMP activities of the drug product site meet the requirements of international quality management systems and market drug regulatory agencies, including those of China, the European Union, FDA, and other mainstream regulations.

Case Studies

Biocatalysis Enables The Efficient Synthesis and Commercial Application of Unnatural Amino Acids (UAAs)

Dry Particle Coating for the Enhancement of API Flowability and Bulk Density

Optimization of Synthetic Process and Metal-Chelation Impurity Control Strategy for Complex Peptide-based RDCs

The Perfect Integration of Immobilized Enzymes and Flow Chemistry: A Powerful Booster for the Commercialization of Biocatalysis Technology

Process Simulation Platform: Enabling Process Development and Scale-up of Active Pharmaceutical Ingredients

Comprehensive Analytical R&D and QC Expertise in Pharmaceutical Development

Preformulation Strategy- Inception to Completion

Facilitating PROTAC Drugs Development with Innovative Processes

Efficacy and Safety - Guidelines for Clinical In-use Stability Studies of ADCs

Continuous Improvement of Project Life Cycle Management, Benefiting Customers by Reducing Total Cost

Molecular Modeling and Data Science for De-risking and Cost- saving of Pharmaceutical Development

Agile and Fast：Enabling Rapid Market Launch of Innovative Drugs from Preclinical to Commercialization in 18 Months

News

News2026-01-08

A Porton Publication in ACS Journal on Polymorphic Crystallization Kinetics Study and Control

News2025-11-27

Porton Pharma Solutions Ranks Among China's Top 100 Premier Pharmaceutical Suppliers and Top 10 in ESG Competitiveness

News2025-08-20

Porton Nominated for the 2025 Sedex Supply Chain Award

News2025-07-31

Porton and Repare Therapeutics Collaborate on OPRD Publication, Demonstrating Strength in Synthetic Process Development and Optimization