案例研究2024-09-18
从研发到三期:肽39AA项目在10个月内完成
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了解更多案例研究2024-11-06
ENT-03 GRC Poster
ENT-03 was predicted to be the mammalian equivalent of trodusquemine, based on knowledge of the bile acids produced in mammals, such as 7-HOCA. The individual C-25 isomers of ENT-03 were prepared and both detected in mouse brain. Trodusquemine and ENT-03 have both demonstrated dramatic effects in obesity and insulin resistance. (25S)-ENT-03 was selected for development for the treatment of diabetes and obesity.
案例研究2024-09-19
ADC药物中有效载荷控制策略与方法分析
抗体偶联药物(Antibody-Drug Conjugate, ADC)作为一种新型抗体药物,通过将靶向特异性抗原的抗体或抗体片段与有效载荷通过连接子偶联而成,兼具传统小分子药物的强效作用和抗体药物的靶向性。