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Case Studies & Whitepapers2026-07-30

Antibody-Oligonucleotide Conjugates: From Conjugation Strategy to Purification and Analytical Control Download

Antibody-Oligo Conjugate (AOC), as an innovative targeted gene therapy biopharmaceutical, effectively integrates the targeting advantages of monoclonal antibodies and the gene regulatory functions of oligonucleotides, helping address key limitations in the inherent of traditional antibody drugs and nucleic acid drugs, and showing substantial clinical value and industrial development potential in the fields of tumors, genetic diseases, and chronic refractory diseases. However, restricted by the
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Case Studies & Whitepapers2026-06-30

FAQ: Applications of Different Synthetic Strategies for Peptide Process Development

Applications of Different Peptide Synthesis Strategies in Process Development

Case Studies & Whitepapers2026-06-25

FAQ: CMC Development Strategy for Oligonucleotides in AOCs

•How to reduce hydrolysis during SMCC conjugation? •Can SMCC conjugate after hydrolytic ring-opening? •How is OAR1 regulated during random SMCC conjugation? •Which strategy is preferred for siRNA linker conjugation: pre-annealing or post-annealing conjugation?
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