Mechanistic Studies in Catalytic Process Development: Supporting Manufacturing Processes and Revealing New Reaction Pathways Download

In pharmaceutical process development, standard optimization tools are invaluable for improving yields and throughput. However, when conventional methods hit a wall, they cannot explain why a reaction behaves unpredictably. This white paper explores how integrating advanced mechanistic studies—combining reaction kinetics, spectroscopy, and computational chemistry—mitigates manufacturing risks, explains unexpected process deviations, and can even uncover entirely new, valuable reaction pathways.