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Small MoleculesSep 21, 2026

PMO Therapeutics: Technical Review and Manufacturing Platform Capabilities

This article offers a systematic overview of PMO drug technology covering underlying principles, manufacturing workflows, and therapeutic prospects.

Small MoleculesAug 27, 2026

Mechanistic Studies in Catalytic Process Development: Supporting Manufacturing Processes and Revealing New Reaction Pathways

Through a case study on loading-dependent chemoselectivity in amide reductions, we demonstrate how first-principles chemical understanding provides the scientific foundation necessary for robust, end-to-end commercial manufacturing control strategies

Biocatalysis

Small MoleculesJun 12, 2026

Biocatalysis Enables the Efficient Synthesis and Commercial Application of Unnatural Amino Acids (UAAs)

Biocatalysis is a pivotal enabler for the sustainable synthesis of unnatural amino acids. By integrating novel enzyme discovery, multi-enzyme cascades and chemo-enzymatic routes, Porton has established practical capabilities to address industry challenges in substrate specificity and enzyme stability. Moving forward, Porton remains dedicated to bridging the gap between laboratory innovation and industrial-scale application, providing customers with reliable, scalable and atom-efficient solutions for UAA production.

Small MoleculesMay 27, 2026

Dry Particle Coating for the Enhancement of API Flowability and Bulk Density

The mechanism of the dry particle coating and a short description of four coating techniques including comil, LabRAM, a high shear mixer and a jet mill are provided.

Small MoleculesFeb 28, 2026

The Perfect Integration of Immobilized Enzymes and Flow Chemistry: A Powerful Booster for the Commercialization of Biocatalysis Technology

Adhering to Porton's core value of “Pursuing Excellence”, the Porton biocatalysis team has designated "enzyme immobilization technology and its industrialization" as a core strategic technology.

Small MoleculesJan 31, 2026

Process Simulation Platform: Enabling Process Development and Scale-up of Active Pharmaceutical Ingredients

The Porton Crystallization team has the capability to perform process simulation of unit operations, including solvent swap, crystallization, filtration and drying.

Small MoleculesJan 15, 2026

A Decisive Milestone for On-time, On-budget Project Delivery

This case study demonstrates how rigorous analytical logic, disciplined execution, and targeted experimentation can resolve complex chromatographic challenges.

Process Chemistry

Small MoleculesDec 08, 2025

Optimizing Process Chemistry for Enhanced Pharmaceutical Manufacturing

Process Chemistry Optimization | Pharma Manufacturing

Preparative Chromatography

Small MoleculesOct 30, 2025

Expert Q&A: How to Efficiently Apply Preparative Chromatography in Drug Research

How to Efficiently Apply Preparative Chromatography in Drug Research

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